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1

Localized Dose Enhancement to Tumor Blood Vessel Endothelial Cells via Megavoltage X-rays and Targeted Gold Nanoparticles: New Potential for External Beam Radiotherapy

Ross I. Berbeco, Wilfred Ngwa, G. Mike Makrigiorgos

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2011

Language:

english

File:

PDF, 642 KB

english, 2011

2

Replacing PCR with COLD-PCR enriches variant DNA sequences and redefines the sensitivity of genetic testing

Li, Jin, Wang, Lilin, Mamon, Harvey, Kulke, Matthew H, Berbeco, Ross, Makrigiorgos, G Mike

Journal:

Nature Medicine

Year:

2008

Language:

english

File:

PDF, 367 KB

english, 2008

3

Impact of beam quality on megavoltage radiotherapy treatment techniques utilizing gold nanoparticles for dose enhancement

Tsiamas, Panagiotis, Liu, Bo, Cifter, Fulya, Ngwa, Wilfred F, Berbeco, Ross I, Kappas, Constantin, Theodorou, Kiriaki, Marcus, Karen, Makrigiorgos, Mike G, Sajo, Erno, Zygmanski, Piotr

Journal:

Physics in Medicine and Biology

Year:

2013

Language:

english

File:

PDF, 1003 KB

english, 2013

4

An amplification and ligation-based method to scan for unknown mutations in DNA

Yuzhi Zhang, Manjit Kaur, Brendan D. Price, Sotirios Tetradis, G. Mike Makrigiorgos

Journal:

Year:

2002

Language:

english

File:

PDF, 245 KB

english, 2002

5

PCR-Based detection of minority point mutations

G. Mike Makrigiorgos

Journal:

Year:

2004

Language:

english

File:

PDF, 226 KB

english, 2004

6

Two-round coamplification at lower denaturation temperature–PCR (COLD-PCR)-based sanger sequencing identifies a novel spectrum of low-level mutations in lung adenocarcinoma

Jin Li, Coren A. Milbury, Cheng Li, G. Mike Makrigiorgos

Journal:

Year:

2009

Language:

english

File:

PDF, 269 KB

english, 2009

7

Measurement of let of orthovoltage x-rays in muscle equivalent plastic

G.Mike Makrigiorgos, Lee M. Chin

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1990

Language:

english

File:

PDF, 138 KB

english, 1990

8

5-[123I]iodo-2′-deoxyuridine in the radiotherapy of an early ascites tumor model

Janina Baranowska-Kortylewicz, G.Mike Makrigiorgos, Annick D. Van Den Abbeele, Robert M. Berman, S.James Adelstein, Amin I. Kassis

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1991

Language:

english

File:

PDF, 1.86 MB

english, 1991

9

Performance of a coumarin-based liquid dosimeter for phantom evaluations of internal dosimetry

Mi-Ae Park, Stephen C. Moore, Naengnoi Limpa-Amara, Zhuang Kang, G. Mike Makrigiorgos

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Year:

2006

Language:

english

File:

PDF, 153 KB

english, 2006

10

Drug Eluting Brachytherapy Spacers: A Potential for Biologically-Enhanced Brachytherapy

Robert A. Cormack, Dattatri Nagesha, Evin Gultepe, Paul Nguyen, Anthony V. D'Amico, Srinivas Sridhar, Mike Makrigiorgos

Journal:

Year:

2010

Language:

english

File:

PDF, 203 KB

english, 2010

11

Biological in situ Dose Painting for Image-Guided Radiation Therapy Using Drug-Loaded Implantable Devices

Robert A. Cormack, Srinivas Sridhar, W. Warren Suh, Anthony V. D'Amico, G. Mike Makrigiorgos

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2010

Language:

english

File:

PDF, 1021 KB

english, 2010

12

Sensitive and quantitative detection of mutations associated with clinical resistance to STI-571

Wei-Hua Liu, G.Mike Makrigiorgos

Journal:

Leukemia Research

Year:

2003

Language:

english

File:

PDF, 112 KB

english, 2003

13

Chitosan Film Containing Poly(D,L-Lactic-Co-Glycolic Acid) Nanoparticles: A Platform for Localized Dual-Drug Release

Dayane B. Tada, Surinder Singh, Dattatri Nagesha, Evan Jost, Craig O. Levy, Evin Gultepe, Robert Cormack, G. Mike Makrigiorgos, Srinivas Sridhar

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 373 KB

english, 2010

14

Novel Visible and Ultraviolet Light Photogeneration of Hydroxyl Radicals by 2-Methyl-4-nitro-quinoline-N-oxide (MNO) and 4, 4′-Dinitro-(2, 2′) bipyridinyl-N, N′-dioxide (DBD)

Stanley W. Botchway, Subrata Chakrabarti, G. Mike Makrigiorgos

Journal:

Photochemistry and Photobiology

Year:

1998

Language:

english

File:

PDF, 644 KB

english, 1998

15

A PCR-based amplification method retaining the quantitative difference between two complex genomes

Makrigiorgos, G. Mike, Chakrabarti, Subrata, Zhang, Yuzhi, Kaur, Manjit, Price, Brendan D.

Journal:

Nature Biotechnology

Year:

2002

Language:

english

File:

PDF, 479 KB

english, 2002

16

Anti-primer quenching-based real-time PCR for simplex or multiplex DNA quantification and single-nucleotide polymorphism genotyping

Li, Jin, Makrigiorgos, G Mike

Journal:

Nature Protocols

Year:

2007

Language:

english

File:

PDF, 215 KB

english, 2007

17

A fluorimetric method for the detection of copper-mediated hydroxyl free radicals in the immediate proximity of DNA

G.Mike Makrigiorgos, Edward Bump, Christine Huang, Janina Baranowska-Kortylewicz, Amin I. Kassis

Journal:

Free Radical Biology and Medicine

Year:

1995

Language:

english

File:

PDF, 828 KB

english, 1995

18

Measurement of hydroxyl radicals catalyzed in the immediate vicinity of DNA by metal-bleomycin complexes

Subrata Chakrabarti, G.Mike Makrigiorgos, Kathryn O'Brien, Edward Bump, Amin I. Kassis

Journal:

Free Radical Biology and Medicine

Year:

1996

Language:

english

File:

PDF, 640 KB

english, 1996

19

Novel Fluorescein-Based Flow-Cytometric Method For Detection of Lipid Peroxidation

G.Mike Makrigiorgos, Amin I Kassis, Ashfaq Mahmood, Edward A Bump, Panos Savvides

Journal:

Free Radical Biology and Medicine

Year:

1997

Language:

english

File:

PDF, 382 KB

english, 1997

20

Fluoresceinated phosphoethanolamine for flow-cytometric measurement of lipid peroxidation

Gautam Maulik, Amin I. Kassis, Panos Savvides, G.Mike Makrigiorgos

Journal:

Free Radical Biology and Medicine

Year:

1998

Language:

english

File:

PDF, 220 KB

english, 1998

21

A comparison of RNA amplification techniques at sub-nanogram input concentration

Julie E Lang, Mark Jesus M Magbanua, Janet H Scott, G Mike Makrigiorgos, Gang Wang, Scot Federman, Laura J Esserman, John W Park, Christopher M Haqq

Journal:

Year:

2009

Language:

english

File:

PDF, 264 KB

english, 2009

22

Stable siRNA-mediated silencing of ATM alters the transcriptional profile of HeLa cells

Shujuan Chen, Gang Wang, G.Mike Makrigiorgos, Brendan D Price

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 1.04 MB

english, 2004

23

Methylation of the ATM promoter in glioma cells alters ionizing radiation sensitivity

Kanaklata Roy, Lilin Wang, G. Mike Makrigiorgos, Brendan D. Price

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 456 KB

english, 2006

24

Detection of lipid peroxidation on erythrocytes using the excimer-forming property of a lipophilic BODIPY fluorescent dye

G.Mike Makrigiorgos

Journal:

Journal of Biochemical and Biophysical Methods

Year:

1997

Language:

english

File:

PDF, 1.01 MB

english, 1997

25

COLD-PCR: a new platform for highly improved mutation detection in cancer and genetic testing

Li, Jin, Makrigiorgos, G. Mike

Journal:

Biochemical Society Transactions

Year:

2009

Language:

english

File:

PDF, 290 KB

english, 2009

26

A stochastic model of cell survival for high-Z nanoparticle radiotherapy

Zygmanski, Piotr, Hoegele, Wolfgang, Tsiamas, Panagiotis, Cifter, Fulya, Ngwa, Wil, Berbeco, Ross, Makrigiorgos, Mike, Sajo, Erno

Journal:

Medical Physics

Year:

2013

Language:

english

File:

PDF, 814 KB

english, 2013

27

In vitro radiosensitization by gold nanoparticles during continuous low-dose-rate gamma irradiation with I-125 brachytherapy seeds

Wilfred Ngwa, Houari Korideck, Amin I. Kassis, Rajiv Kumar, Srinivas Sridhar, G. Mike Makrigiorgos, Robert A. Cormack

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2013

Language:

english

File:

PDF, 294 KB

english, 2013

28

DNA Damage Enhancement from Gold Nanoparticles for Clinical MV Photon Beams

Berbeco, Ross I., Korideck, Houari, Ngwa, Wilfred, Kumar, Rajiv, Patel, Janki, Sridhar, Srinivas, Johnson, Sarah, Price, Brendan D., Kimmelman, Alec, Makrigiorgos, G. Mike

Journal:

Radiation Research

Year:

2012

Language:

english

File:

PDF, 377 KB

english, 2012

29

The effect of flattening filter free delivery on endothelial dose enhancement with gold nanoparticles

Detappe, Alexandre, Tsiamas, Panagiotis, Ngwa, Wilfred, Zygmanski, Piotr, Makrigiorgos, Mike, Berbeco, Ross

Journal:

Medical Physics

Year:

2013

Language:

english

File:

PDF, 437 KB

english, 2013

30

Applying gold nanoparticles as tumor-vascular disrupting agents during brachytherapy: estimation of endothelial dose enhancement

Ngwa, Wilfred, Makrigiorgos, G Mike, Berbeco, Ross I

Journal:

Physics in Medicine and Biology

Year:

2010

Language:

english

File:

PDF, 534 KB

english, 2010

31

Gold nanoparticle-aided brachytherapy with vascular dose painting: Estimation of dose enhancement to the tumor endothelial cell nucleus

Ngwa, Wilfred, Makrigiorgos, G. Mike, Berbeco, Ross I.

Journal:

Medical Physics

Year:

2012

Language:

english

File:

PDF, 1.24 MB

english, 2012

32

Facile synthesis of PEGylated PLGA nanoparticles encapsulating doxorubicin and its in vitro evaluation as potent drug delivery vehicle

Kumar, Rajiv, Kulkarni, Apurva, Nabulsi, Jude, Nagesha, Dattatri K., Cormack, Robert, Makrigiorgos, Mike G., Sridhar, Srinivas

Journal:

Drug Delivery and Translational Research

Year:

2013

Language:

english

File:

PDF, 503 KB

english, 2013

33

Precision and Performance Characteristics of Bisulfite Conversion and Real-Time PCR (MethyLight) for Quantitative DNA Methylation Analysis

Ogino, Shuji, Kawasaki, Takako, Brahmandam, Mohan, Cantor, Mami, Kirkner, Gregory J., Spiegelman, Donna, Makrigiorgos, G. Mike, Weisenberger, Daniel J., Laird, Peter W., Loda, Massimo, Fuchs, Charles

Journal:

The Journal of Molecular Diagnostics

Year:

2006

Language:

english

File:

PDF, 251 KB

english, 2006

34

COLD-PCR: improving the sensitivity of molecular diagnostics assays

Milbury, Coren A, Li, Jin, Liu, Pingfang, Makrigiorgos, G Mike

Journal:

Expert Review of Molecular Diagnostics

Year:

2011

Language:

english

File:

PDF, 527 KB

english, 2011

35

Multiplex Amplification Coupled with COLD-PCR and High Resolution Melting Enables Identification of Low-Abundance Mutations in Cancer Samples with Low DNA Content

Milbury, Coren A., Chen, Clark C., Mamon, Harvey, Liu, Pingfang, Santagata, Sandro, Makrigiorgos, G. Mike

Journal:

The Journal of Molecular Diagnostics

Year:

2011

Language:

english

File:

PDF, 2.35 MB

english, 2011

36

Derivation of Radiation Quality Average Parameters in Neutron-γ Radiation Fields with the High-Pressure Ionization Chamber: Theory and Practice

Gerassimos Mike Makrigiorgos

Journal:

Radiation Research

Year:

1989

Language:

english

File:

PDF, 1.27 MB

english, 1989

37

Response to the Comments of E. L. Powers

G. Mike Makrigiorgos

Journal:

Radiation Research

Year:

1995

Language:

english

File:

PDF, 187 KB

english, 1995

38

Whole Genome Amplification of Plasma-Circulating DNA Enables Expanded Screening for Allelic Imbalance in Plasma

Li, Jin, Harris, Lyndsay, Mamon, Harvey, Kulke, Matthew H., Liu, Wei-Hua, Zhu, Penny, Mike Makrigiorgos, G.

Journal:

The Journal of Molecular Diagnostics

Year:

2006

Language:

english

File:

PDF, 687 KB

english, 2006

39

Radiation dose enhancement of gadolinium-based AGuIX nanoparticles on HeLa cells

Luchette, Matthew, Korideck, Houari, Makrigiorgos, Mike, Tillement, Olivier, Berbeco, Ross

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 617 KB

english, 2014

40

MOSFET Assessment of Radiation Dose Delivered to Mice Using the Small Animal Radiation Research Platform (SARRP)

Ngwa, Wilfred, Korideck, Houari, Chin, Lee M., Makrigiorgos, G. Mike, Berbeco, Ross I.

Journal:

Radiation Research

Year:

2011

Language:

english

File:

PDF, 643 KB

english, 2011

41

Generation of Hydroxyl Radicals by Nucleohistone-Bound Metal–Adriamycin Complexes

Chakrabarti, Subrata, Mahmood, Ashfaq, Kassis, Amin I., Bump, Edward A., Jones, Alun G., Makrigiorgos, G. Mike

Journal:

Free Radical Research

Year:

1996

Language:

english

File:

PDF, 1012 KB

english, 1996

42

NRAS mutations with low allele burden have independent prognostic significance for patients with lower risk myelodysplastic syndromes

Murphy, D M, Bejar, R, Stevenson, K, Neuberg, D, Shi, Y, Cubrich, C, Richardson, K, Eastlake, P, Garcia-Manero, G, Kantarjian, H, Ebert, B L, Mike Makrigiorgos, G

Journal:

Year:

2013

Language:

english

File:

PDF, 857 KB

english, 2013

43

Targeted radiotherapy with gold nanoparticles: current status and future perspectives

Ngwa, Wilfred, Kumar, Rajiv, Sridhar, Srinivas, Korideck, Houari, Zygmanski, Piotr, Cormack, Robert A, Berbeco, Ross, Makrigiorgos, G Mike

Journal:

Year:

2014

Language:

english

File:

PDF, 6.43 MB

english, 2014

44

Build-up and surface dose measurements on phantoms using micro-MOSFET in 6 and 10 MV x-ray beams and comparisons with Monte Carlo calculations

Xiang, Hong F., Song, Jun S., Chin, David W. H., Cormack, Robert A., Tishler, Roy B., Makrigiorgos, G. Mike, Court, Laurence E., Chin, Lee M.

Journal:

Medical Physics

Year:

2007

Language:

english

File:

PDF, 1.29 MB

english, 2007

45

Image-guided radiotherapy platform using single nodule conditional lung cancer mouse models

Herter-Sprie, Grit S., Korideck, Houari, Christensen, Camilla L., Herter, Jan M., Rhee, Kevin, Berbeco, Ross I., Bennett, David G., Akbay, Esra A., Kozono, David, Mak, Raymond H., Mike Makrigiorgos, G

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 1.10 MB

english, 2014

46

Gold nanoparticle enhancement of stereotactic radiosurgery for neovascular age-related macular degeneration

Ngwa, Wilfred, Makrigiorgos, G Mike, Berbeco, Ross I

Journal:

Physics in Medicine and Biology

Year:

2012

Language:

english

File:

PDF, 603 KB

english, 2012

47

New potential for enhancing concomitant chemoradiotherapy with FDA approved concentrations of cisplatin via the photoelectric effect

Altundal, Yucel, Cifter, Gizem, Detappe, Alexandre, Sajo, Erno, Tsiamas, Panagiotis, Zygmanski, Piotr, Berbeco, Ross, Cormack, Robert A., Makrigiorgos, Mike, Ngwa, Wilfred

Journal:

Year:

2015

Language:

english

File:

PDF, 727 KB

english, 2015

48

Nanoparticle-Based Brachytherapy Spacers for Delivery of Localized Combined Chemoradiation Therapy

Kumar, Rajiv, Belz, Jodi, Markovic, Stacey, Jadhav, Tej, Fowle, William, Niedre, Mark, Cormack, Robert, Makrigiorgos, Mike G., Sridhar, Srinivas

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2015

Language:

english

File:

PDF, 1.52 MB

english, 2015

49

Brachytherapy Application With In Situ Dose Painting Administered by Gold Nanoparticle Eluters

Sinha, Neeharika, Cifter, Gizem, Sajo, Erno, Kumar, Rajiv, Sridhar, Srinivas, Nguyen, Paul L., Cormack, Robert A., Makrigiorgos, G. Mike, Ngwa, Wilfred

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2015

Language:

english

File:

PDF, 1.37 MB

english, 2015

50

[IEEE 2014 40th Annual Northeast Bioengineering Conference (NEBEC) - Boston, MA, USA (2014.4.25-2014.4.27)] 2014 40th Annual Northeast Bioengineering Conference (NEBEC) - Localized tumor delivery of radiosensitizers and chemotherapeutics using ‘INCeRT’ implants

Belz, Jodi, Kumar, Rajiv, Markovic, Stacey, Niedre, Mark, Sridhar, Srinivas, Nguyen, Paul, Niedre, Mark, Damico, Anthony, Makrigiorgos, Mike, Cormack, Robert

Year:

2014

Language:

english

File:

PDF, 2.88 MB

english, 2014

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